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Serono computer generated randomisation list
Computer Generated Randomisation List, supplied by Serono, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/computer+generated+randomisation+list/computer+generated+list+randomisation/pmc10687854-2344-10-16
Average 86 stars, based on 1 article reviews
computer generated randomisation list - by Bioz Stars, 2026-10
86/100 stars

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Sequencing:

Article Title: Immunomodulators and immunosuppressants for multiple sclerosis: a network meta‐analysis
Article Snippet: .. Random sequence generation (selection bias) , Low risk , " Computer generated randomisation list provided by Serono, stratified by center; treatments were equally allocated with a block size of six ". Page 1497. .. Allocation concealment (selection bias) , Unclear risk , "The block size was not revealed to the investigators. T he manufacturer labelled containers of study medication with patient identification numbers based on the randomisation list, and patients received the medication labelled with their numbers. " Page 1497.

Article Title: Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis
Article Snippet: Relapses were assessed also as adverse events SPECTRIMS 2001 Methods RCT Participants Age: 18-55 years; clinical definite SPMS; progression ≥ 1 EDSS over the previous 2 years, with or without superimposed relapses before randomisation; EDSS 3.0-6.5; mean disease duration 14 years Interventions IFNß -1a (Rebif ) 22 μg subcutaneous three times/week for 3 years (n. 209) IFNß -1a (Rebif ) 44 μg subcutaneous three times/week for 3 years (n. 204) Placebo (unspecified) for 3 years (n. 205) Outcomes Progression at 24 and 36 months Notes Funding: Serono International, Geneva, Switzerland .. Bias Authors’ judgement Support for judgement Random sequence generation (selection bias) Low risk “Computer generated randomisation list provided by Serono, stratified by center; treatments were equally allocated with a block size of six”. ..

Selection:

Article Title: Immunomodulators and immunosuppressants for multiple sclerosis: a network meta‐analysis
Article Snippet: .. Random sequence generation (selection bias) , Low risk , " Computer generated randomisation list provided by Serono, stratified by center; treatments were equally allocated with a block size of six ". Page 1497. .. Allocation concealment (selection bias) , Unclear risk , "The block size was not revealed to the investigators. T he manufacturer labelled containers of study medication with patient identification numbers based on the randomisation list, and patients received the medication labelled with their numbers. " Page 1497.

Article Title: Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis
Article Snippet: Relapses were assessed also as adverse events SPECTRIMS 2001 Methods RCT Participants Age: 18-55 years; clinical definite SPMS; progression ≥ 1 EDSS over the previous 2 years, with or without superimposed relapses before randomisation; EDSS 3.0-6.5; mean disease duration 14 years Interventions IFNß -1a (Rebif ) 22 μg subcutaneous three times/week for 3 years (n. 209) IFNß -1a (Rebif ) 44 μg subcutaneous three times/week for 3 years (n. 204) Placebo (unspecified) for 3 years (n. 205) Outcomes Progression at 24 and 36 months Notes Funding: Serono International, Geneva, Switzerland .. Bias Authors’ judgement Support for judgement Random sequence generation (selection bias) Low risk “Computer generated randomisation list provided by Serono, stratified by center; treatments were equally allocated with a block size of six”. ..

Generated:

Article Title: Immunomodulators and immunosuppressants for multiple sclerosis: a network meta‐analysis
Article Snippet: .. Random sequence generation (selection bias) , Low risk , " Computer generated randomisation list provided by Serono, stratified by center; treatments were equally allocated with a block size of six ". Page 1497. .. Allocation concealment (selection bias) , Unclear risk , "The block size was not revealed to the investigators. T he manufacturer labelled containers of study medication with patient identification numbers based on the randomisation list, and patients received the medication labelled with their numbers. " Page 1497.

Article Title: Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis
Article Snippet: Relapses were assessed also as adverse events SPECTRIMS 2001 Methods RCT Participants Age: 18-55 years; clinical definite SPMS; progression ≥ 1 EDSS over the previous 2 years, with or without superimposed relapses before randomisation; EDSS 3.0-6.5; mean disease duration 14 years Interventions IFNß -1a (Rebif ) 22 μg subcutaneous three times/week for 3 years (n. 209) IFNß -1a (Rebif ) 44 μg subcutaneous three times/week for 3 years (n. 204) Placebo (unspecified) for 3 years (n. 205) Outcomes Progression at 24 and 36 months Notes Funding: Serono International, Geneva, Switzerland .. Bias Authors’ judgement Support for judgement Random sequence generation (selection bias) Low risk “Computer generated randomisation list provided by Serono, stratified by center; treatments were equally allocated with a block size of six”. ..

Blocking Assay:

Article Title: Immunomodulators and immunosuppressants for multiple sclerosis: a network meta‐analysis
Article Snippet: .. Random sequence generation (selection bias) , Low risk , " Computer generated randomisation list provided by Serono, stratified by center; treatments were equally allocated with a block size of six ". Page 1497. .. Allocation concealment (selection bias) , Unclear risk , "The block size was not revealed to the investigators. T he manufacturer labelled containers of study medication with patient identification numbers based on the randomisation list, and patients received the medication labelled with their numbers. " Page 1497.

Article Title: Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis
Article Snippet: Relapses were assessed also as adverse events SPECTRIMS 2001 Methods RCT Participants Age: 18-55 years; clinical definite SPMS; progression ≥ 1 EDSS over the previous 2 years, with or without superimposed relapses before randomisation; EDSS 3.0-6.5; mean disease duration 14 years Interventions IFNß -1a (Rebif ) 22 μg subcutaneous three times/week for 3 years (n. 209) IFNß -1a (Rebif ) 44 μg subcutaneous three times/week for 3 years (n. 204) Placebo (unspecified) for 3 years (n. 205) Outcomes Progression at 24 and 36 months Notes Funding: Serono International, Geneva, Switzerland .. Bias Authors’ judgement Support for judgement Random sequence generation (selection bias) Low risk “Computer generated randomisation list provided by Serono, stratified by center; treatments were equally allocated with a block size of six”. ..



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